Wideband Handheld Confocal Raman Skin Analyzer

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Products / Microscopes /High-end Microscopes /Wideband Handheld Confocal Raman Skin Analyzer /

Wideband Handheld Confocal Raman Skin Analyzer

Overview Specifications Related Products Order Now!

DermDive - The first portable wideband confocal Raman Skin Analyzer in the world!

Confocal Raman Spectroscopy (CRS) is a groundbreaking optical technology used extensively for biological tissue analysis, prized for its noninvasive approach, pinpoint accuracy and comprehensive biochemical insights. Despite its advantages, traditional CRS systems are encumbered by limited detection, cumbersome designs, reduced flexibility, slow data collection, and escalated costs.

To counter these challenges, we are developed a compact, handheld CRS system, aptly named “DermDive”. DermDive is the world first wideband handheld confocal Raman skin analyzer covering both finger-print region (FP, 450–1750 cm–1) and high wavenumber region (HW, 2800–3800 cm–1) with a handheld probe. DermDive has adjustable and user-defined measurement time suitable for various applications. It provides molecular information at different skin layers noninvasively, up to 200.

DermDive is designed to be user-friendly for skin diagnosis on various parts of human body, thanks to its flexibility.

Features

A harmonized integration of single or dual-wavelength lasers through an efficient (>90%) wavelength combiner, enabling near-instantaneous excitation.
The groundbreaking Raman Spectra Separation Algorithm (PRSSA), a pioneer in spectrum separation, harnessing the maximum a posteriori probability (MAP) estimate. This offers an astounding >99% accuracy, as evidenced in both laboratory simulations and real-time human skin analyses.
A notable reduction in data collection time, outpacing conventional CRS systems by over 50%.

√ Noninvasive √ Depth profiling

√ Fast √ Safe

√ User friendly √ Fingerprint region + high wavenumber region

√ Handheld

Light Path Diagram

Light Path Diagram

Available Raman Spectra Database

Natural moisturizing factors (NMF), water, ceramide, keratin, lactic acid, urea, urocanic acid at different depths.

DermDive_Product_Ins

Product specifications and Brochures

Product Brochure Link:

Parameter	DermDive
Detection Range	FP: 450 – 1750cm^-1; HW: 2800-3750cm^-1
Axial Resolution	10um~20um
Stratum Corneum Thickness	up to 200nm
Sensitivity	60dB
Scanning Time	2-10s/depth
Probe Size	~12 cm × 6 cm × 5 cm
Probe Weight	~800g
Device Size	~ H: 1m, W: 50cm, L: 50cm
Device Weight	~ 40kg
Raman Library	Natural Moisturizing Factors(NMF): Pyrrolidone carboxylic acid Ornithine Serine Proline Glycine Histidine Alanine Ceramide Keratin Lactic acid Urea Urocanic acid Water content
Other Parameters	Stratum corneum thickness Penetration depth of a certain chemical Other chemicals of interest upon request

Benchmarking with RiverD Benchtop CRS

Spectra of DermDive and RiverD at single depth and Various depths. Spectra qualities are comparable.

Optical Performance Characterization

Axial resolutions and sensitivities with different optical components.

Name	Model	Wavelength Range	Detector	Resolution	Noise Ratio	Dynamic Range
High Resolution Spectrometer	L Sereis	200-1100nm	Hamamatsu，S11639，2048 pixels	<1nm customizable	500:1	2000:1
High Resolution Spectrometer	H Series	200-1100nm	Hamamatsu，S11639，2048 pixels	<1nm customizable	500:1	2000:1
Back Illuminated Spectrometer	M Series	200-1100nm	Hamamatsu，S10420，64×2048 pixels	<1nm customizable	800:1	5000:1
Hi Sensitivity Cooled Spectrometer	MC Serie	200-1100nm	Hamamatsu，S7031，64×1044 pixels	<1nm customizable	1000:1	10000:1
Handheld Raman System	RM	785/1064nm	Band Range 200-3200cm^-1/ 200-2500cm^-1	6 - 8 cm^-1
Portable Tabletop Raman System	RMT EZ	785nm	Band Range 200-3200cm^-1	7 cm^-1 typical
Portable Tabletop Raman System	RMT	532/785/1064nm	Band Range 200-3200cm^-1/200-1800cm^-1	8 - 9 cm^-1 typical

	Laser Scanning Confocal Microscope,
	High Speed Line Scan Confocal Microscope
	Fluorescence / Photoluminescence Microscope
	Time Correlated Single Photon Counting (Solution)

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Compare	Model		Drawings & Specs	Availability	Reference Price (USD)
		DermDive Wideband Handheld Confocal Raman Skin Analyzer, Detection Range: FP: 450 – 1750cm-1; HW: 2800-3750cm-1, Axial Resolution: 10um~20um, Sensitivity: 60dB, Scanning Time: 2-10s/depth		6-8 Weeks	Request for quote

DermDive - Parameter

DermDive - Download

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