The Multi-channel CW Multi-Mode lasers (4-in-1 lasers) include four different wavelengths (405nm/488nm/525nm/628nm) that integrate a laser diode, laser cavity, fiber-coupled optics, laser power supply, and LD current. It is designed for laser scanning confocal microscopy systems.

The 4-in-1 laser in a laser scanning confocal microscope system is a special laser system used in biomedical research and clinical applications. It combines four different wavelengths of lasers to provide a variety of excitation light sources. Laser scanning confocal microscopy is a high-resolution microscopy technique that obtains three-dimensional images of cells and tissues by scanning and focusing with a laser beam. The 4-in-1 laser provides different wavelengths of laser light to a laser scanning confocal microscope system to excite different fluorochromes or labels, allowing samples to be observed and studied under the microscope.

Different wavelengths of lasers can interact with different fluorochromes or markers, enabling the visualization and localization of different cellular and molecular structures. For example, the 405nm laser is typically used to excite UV dyes, 488nm is used for fluorescein and green fluorescent proteins, the 525nm laser is used for yellow fluorescent proteins and red fluorescent dyes, and the 640nm laser is used for fluorescent proteins and infrared dyes.

The advantage of the 4-in-1 laser system is that it provides a multi-wavelength laser light source that can excite multiple fluorochromes or labels at the same time, providing a more comprehensive picture in a single experiment. This has important implications for multicolor fluorescence imaging, colocalization, and co-expression studies of cells and tissues.

Laser power supply front panel

Laser power supply rear panel

Features

Application

Using the different wavelength lasers provided by the four-in-one laser, the position and distribution of cell organelles such as the nucleus, mitochondria, and Golgi apparatus can be labeled and observed, which help to study cell function and interactions.

Using the different wavelength lasers provided by the four-in-one laser, the fluorescence signals of multiple markers can be simultaneously observed and analyzed to understand their co-localization and co-expression in cells or tissues.

Using the laser light source provided by the four-in-one laser to excite specific fluorescent markers in neurons, such as calcium indicators, neuronal excitability and synaptic transmission processes can be observed and recorded through laser confocal microscope.

 In cell culture models, the laser light source provided by the four-in-one laser can be used to observe and analyze changes in cell morphology and structure to evaluate he effects and efficacy of drugs on cells.

Using the laser light source provided by the four-in-one laser, the details of cell structures, pathological changes and tumor metastasis in tissue samples can be observed and analyzed, providing pathologists with more accurate diagnostic and treatment decision-making basis.

• 1 Display screen
• 2 Potentiometer
• 3 Status display light
• 4 Key switches

• 1 Optical Fiber
• 2 100-240VAC
• 3 SIGNAL IN
• 4 Fan
• 5 485 communication protocol
• 6 Switch
  

Set the power switch ON the rear panel of the laser power supply to "ON".

The red power indicator is steady on, indicating that the power supply is connected.

The blue indicator "Power" and red Alarm indicator "Alarm" are on at the same time.

The red alarm indicator "alarm" will be automatically extinguished after three seconds

In operation

405/445/470/520/

528/555/640(nm)

405/445/470/520/

528/555/640(nm)

Inverted or

Upright 

Inverted or

Upright 

Don't have time to search the products one by one? No worries. you can download the full range of SIMTRUM Product Line Cards.

Click it now.

Want to stay closer to the Market Dynamics and Technological 

Developments? Just take 5 seconds to Sign In as a member of 

SIMTRUM, we will bring you the most up-to-date news. 

(Sign in button on the top right of the screen).